منابع مشابه
Tachometer for Reverse Cholesterol Transport?
M any clinical and epidemiological studies, as well as meta-analyses thereof, have shown the inverse relationship of high-density lipoprotein cholesterol (HDL-C) and apoliopoprotein (apo) A-I plasma levels with the risk of coronary artery disease. HDL particles and their protein and lipid components exert diverse antioxidative, antiinflammatory, antithrombotic, and cytoprotective effects in vit...
متن کاملReverse cholesterol transport and atherosclerosis regression.
Cholesterol is the major component of atherosclerotic plaque. Cholesterol accumulation within atherosclerotic plaque occurs when cholesterol influx into the arterial wall (from apoB-containing lipoproteins) exceeds cholesterol efflux. Increased influx of cholesterol into the arterial wall is accompanied by an increased influx of monocytes/macrophages,1 which take up oxidized and aggregated LDL ...
متن کاملA New Frontier for Reverse Cholesterol Transport
Numerous epidemiological studies have demonstrated that high-density lipoprotein cholesterol (HDL-C) levels are inversely associated with cardiovascular risk. However, despite intense efforts to develop new pharmacological strategies to increase HDL-C levels, such as with niacin and cholesteryl ester transfer protein inhibitors, few robust associations with improved clinical outcomes have been ...
متن کاملPhysical fitness and reverse cholesterol transport.
BACKGROUND Physical exercise is associated with a decreased risk of cardiovascular disease, which may be partly caused by the effect of exercise on the lipoprotein profile. The most consistent effect of exercise on lipoprotein metabolism is an increase in high-density lipoprotein (HDL). METHODS AND RESULTS Parameters of reverse cholesterol transport (RCT) in 25 endurance-trained male athletes...
متن کاملInflammation impairs reverse cholesterol transport in vivo.
BACKGROUND Inflammation is proposed to impair reverse cholesterol transport (RCT), a major atheroprotective function of high-density lipoprotein (HDL). The present study presents the first integrated functional evidence that inflammation retards numerous components of RCT. METHODS AND RESULTS We used subacute endotoxemia in the rodent macrophage-to-feces RCT model to assess the effects of inf...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cor et Vasa
سال: 2006
ISSN: 0010-8650,1803-7712
DOI: 10.33678/cor.2006.037